Collman’s Reagent

Collman’s Reagent

Overall Score4
  • Generality
  • Reagent Availability
  • Experimental User Friendliness
  • General Characteristics

Disodium tetracarbonylferrate is generally referred to as the Collman reagent. It reacts with alkyl halides to give corresponding aldehydes and ketones.

  • General References

  • History

Na2[Fe(CO)4] complex and its synthetic applications were reported by James Collman in the 1970’s.


  • Reaction Mechanism


  • Examples

Unsymmetrical ketones can be synthesized by reacting two benzyl halides with the Collman’s reagent sequentially.[1]


  • Experimental Procedure

  • Experimental Tips

  • References

[1] Potter, R. G.; Hughes, T. S. Org. Lett. 2007, 9, 1187. DOI: 10.1021/ol0629770

  • Related Reactions

  • Related Books

  • External Links

Disodium Tetracarbonylferrate – Wikipedia

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