General Characteristics Thioesters can be converted into aldehydes directly without going through complete reduction to alcohols. By the Fukuyama procedure, the reduction can be effected under very ...
Tag Archives: synthesis of aldehydes
Pummerer Rearrangement
General Characteristics The treatment of sulfoxides with acid anhydrides or acid chlorides brings about a reaction called the Pummerer rearrangement, which gives α-acyloxythioethers. The rearranged ...
Albright-Goldman Oxidation
General Characteristics The Swern-type oxidation of alcohols using acetic anhydride as the activator of DMSO. The reaction times are relatively long (12-24 h). This reaction is useful for the ...
Jones Oxidation
General Characteristics The Jones oxidation is one of the most fundamental reactions used to oxidize alcohol compounds. The reagents do not react with alkenes and alkynes and oxidize only alcohols. ...
Partial Reduction of Esters, Amides, and Nitriles with Metal Hydride Reagents
General Characteristics Esters, amides, and nitriles are reduced to aldehydes (without overreduction) using appropriate metal hydride reagents at low temperatures. DIBAL and Red-Al are used commonly ...
TPAP (Ley-Griffith) Oxidation
General Characteristics The oxidation of alcohols to aldehydes or ketones can be catalyzed by TPAP (nPr4N+RuO4–; TetraPropylAmmonium Perruthenate) which is air- and moisture-tolerant and also ...