Reliable papers summarizing NMR data of various solvents in various heavy solvents are indispensable to organic chemists. In this post, four papers that contain NMR chemical shifts are presented: Why ...
Posts by Category: OrganicChem
Chemoinformatically Guided Discovery of Chiral Catalysts
Prof. Scott E. Denmark et al. at the University of Illinois used three-dimensional molecular structures to enable machine learning to predict selectivity in asymmetric catalysis in 2019.[1] Later in ...
Process Mass Intensity, PMI
Process Mass Intensity (PMI) is the total mass of material used to produce a product of a given mass, determined in units of mass of input material (e.g., kg) per mass of product (e.g., kg). The PMI ...
Complex Acid Chlorides from Unsaturated Hydrocarbons
Morandi at Max-Planck-Institut für Kohlenforschung developed an exchange reaction for producing functionalized acid chlorides． “CO- and HCl-free synthesis of acid chlorides from unsaturated ...
Ugi Reaction for Alternating Peptides
Koyama and Gudeangadi at Toyama Prefectural University developed an Ugi-reaction-based synthetic method of producing alternating peptides． “One-pot synthesis of alternating peptides exploiting a new ...
Arylation at Lysine Residues
Pentelute and Buchwald et al. at MIT developed a method for chemoselective functionalization of peptides． “Palladium-Mediated Arylation of Lysine in Unprotected Peptides” Lee, H.-G.; Lautrette, G.; ...
Near-Infrared Light Activated Azo-BF2 Switches
Yang, Y.; Hughes, R. P.; Aprahamian, I. J. Am. Chem. Soc. 2014, 136 ,13190–13193 DOI: 10.1021/ja508125n ABSTRACT: Increasing the electron density in BF2- coodinated azo compounds through ...
Metal-Free Hydrogenation Catalyzed by an Air-Stable Borane: Use of Solvent as a Frustrated Lewis Base
Scott, D. J.; Fuchter, M. J.; Ashley, A. E. Angew. Chem. Int. Ed. 53, 2014. 53, 10218. DOI: 10.1002/anie.201405531 In recent years “frustrated Lewis pairs” (FLPs) have been shown to be effective ...
Far-Red Fluorescence Probe for Monitoring Singlet Oxygen during Photodynamic Therapy
S, Kim.;T, Tachikawa.; M, Fujitsuka.; T, Majima. J. Am. Chem. Soc. 2014. 136, 11707. DOI: 10.1021/ja504279r Singlet oxygen (1O2), molecular oxygen in thelowest excited state, has a critical role in ...
Arylazopyrazoles: Azoheteroarene Photoswitches Offering Quantitative Isomerization and Long Thermal Half-Lives
Weston. C. E; Richardson, R.; Haycock, P.; White, A.; Fuchter, M. J. Am. Chem. Soc. 2014, 136, 11878. DOI: 10.1021/ja505444d Arylazopyrazoles, a novel class of five-membered azo photoswitches, ...