Alexey N. Butkevich, Grazv̌ydas Lukinavicǐus, Elisa D’Este, and Stefan W. Hell. J. Am. Chem. Soc., 2017, 139, 12378. DOI:10.1021/jacs.7b06412 Abstract Abstract: We designed cell-permeant ...
Posts by Category: ChemicalBiology
Arylation at Lysine Residues
Pentelute and Buchwald et al. at MIT developed a method for chemoselective functionalization of peptides． “Palladium-Mediated Arylation of Lysine in Unprotected Peptides” Lee, H.-G.; Lautrette, G.; ...
An Excimer-Based, Turn-On Fluorescent Sensor for the Selective Detection of Diphosphorylated Proteins in Aqueous Solution and Polyacrylamide Gels
Kraskouskaya, D.; Bancerz, M.; Soor, H. S.; Gardiner, J. E.; Gunning, P. T. Am. Chem. Soc., 2014, 136, 1234–1237 DOI: 10.1021/ja411492k ABSTRACT: Protein phosphorylation is a ubiquitous ...
Lighting Up Individual DNA Damage Sites by In Vitro Repair Synthesis
Zirkin, S.; Fishman, S.; Sharim, H.; Michaeli, Y.; Don, J.; Ebenstein, Y. J. Am. Chem. Soc., 2014, 136, 7771–7776. DOI: 10.1021/ja503677n DNA damage and repair are linked to fundamentalbiological ...
Dual Changes in Conformation and Optical Properties of Fluorophores within a Metal−Organic Framework during Framework Construction and Associated Sensing Event
W, Cho.; H, Lee.; G, Choi.;S, Choi.; M, Oh. J. Am. Chem. Soc., 2014, 136, 12201. DOI: 10.1021/ja504204d Microsized chemosensor particle (CPP-16, CPP means coordination polymer particle), which is ...
A spontaneously blinking fluorophore based on intramolecular spirocyclization for live-cell super-resolution imaging
Uno, S. Kamiya, M..; Yoshihara, T.; Sugawara, K.; Okabe, K.; Tarhan, M. C.; Fujita H.; Funatsu. T.; Okada. Y.; Tobita, S.; Urano., Y. Nat. Chem. 2014, ASAP. DOI:10.1038/nchem.2002 Single-molecule ...
Photocaging of Carboxylic Acids: A Modular Approach
Szymanski, W.; Velema, W. A.; Feringa, B. L. Angew. Chem. Int. Ed. 53, 2014. Early View. DOI: 10.1002/anie.201402665 Photocaged compounds are important tools for studying and regulating multiple ...
Turn-ON fluorescent affinity labeling using a small bifunctional O-nitrobenzoxadiazole unit
Yamaguchi, T.; Asanuma, M.; Nakanishi, S.;Saito Y.;,Okazaki, M.; Dodoab, K. Sodeoka, M. Chem. Sci., 2014, Advance Article DOI: 10.1039/C3SC52704B Affinity labeling has become a powerful tool to ...