Prof. Scott E. Denmark et al. at the University of Illinois used three-dimensional molecular structures to enable machine learning to predict selectivity in asymmetric catalysis in 2019.[1] Later in ...
Posts by Category: Papers
Process Mass Intensity, PMI
Process Mass Intensity (PMI) is the total mass of material used to produce a product of a given mass, determined in units of mass of input material (e.g., kg) per mass of product (e.g., kg). The PMI ...
Cell-Permeant Large Stokes Shift Dyes for Transfection-Free Multicolor Nanoscopy
Alexey N. Butkevich, Grazv̌ydas Lukinavicǐus, Elisa D’Este, and Stefan W. Hell. J. Am. Chem. Soc., 2017, 139, 12378. DOI:10.1021/jacs.7b06412 Abstract Abstract: We designed cell-permeant ...
Complex Acid Chlorides from Unsaturated Hydrocarbons
Morandi at Max-Planck-Institut für Kohlenforschung developed an exchange reaction for producing functionalized acid chlorides． “CO- and HCl-free synthesis of acid chlorides from unsaturated ...
Ugi Reaction for Alternating Peptides
Koyama and Gudeangadi at Toyama Prefectural University developed an Ugi-reaction-based synthetic method of producing alternating peptides． “One-pot synthesis of alternating peptides exploiting a new ...
Arylation at Lysine Residues
Pentelute and Buchwald et al. at MIT developed a method for chemoselective functionalization of peptides． “Palladium-Mediated Arylation of Lysine in Unprotected Peptides” Lee, H.-G.; Lautrette, G.; ...
Near-Infrared Light Activated Azo-BF2 Switches
Yang, Y.; Hughes, R. P.; Aprahamian, I. J. Am. Chem. Soc. 2014, 136 ,13190–13193 DOI: 10.1021/ja508125n ABSTRACT: Increasing the electron density in BF2- coodinated azo compounds through ...
An Excimer-Based, Turn-On Fluorescent Sensor for the Selective Detection of Diphosphorylated Proteins in Aqueous Solution and Polyacrylamide Gels
Kraskouskaya, D.; Bancerz, M.; Soor, H. S.; Gardiner, J. E.; Gunning, P. T. Am. Chem. Soc., 2014, 136, 1234–1237 DOI: 10.1021/ja411492k ABSTRACT: Protein phosphorylation is a ubiquitous ...
Small-Molecule Labeling of Live Cell Surfaces for Three-Dimensional Super-Resolution Microscopy
Lee, M.K.; Rai, P.; Williams, J.; Twieg, R. J.; Moerner, W. E. J. Am. Chem. Soc. 2014, 136, 14003–14006 DOI: 10.1021/ja508028h Precise imaging of the cell surface of fluorescently labeled bacteria ...
Photoelectric Signal Conversion by Combination of Electron-Transfer Chain Catalytic Isomerization and Photoisomerization on Benzodimethyldihydropyrenes
Kishida, M.; Kusamoto, T.; Nishihara, H. J. Am. Chem. Soc., 2014, 136, 4809. DOI: 10.1021/ja412528d Photochromic benzocyclophanediene showed oxidation-triggered isomerization to form ...