Tag Archives: C-H oxidation

Oxidation with Dioxiranes

Oxidation with Dioxiranes

General Characteristics Dimethyldioxirane (DMDO), prepared from acetone and Oxone®, is used frequently to oxidize alkenes to epoxides. Methyl(trifluoromethyl)dioxirane (TFDO) is about 600 times more ...

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Kharasch-Sosnovsky Oxidation

Kharasch-Sosnovsky Oxidation

General Characteristics Allylic C-H oxidation can be effected using acylperoxide under copper-catalyzed conditions. The alkene starting materials are usually used in excess. The terminal olefins are ...

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C-H Oxidation with NHPI Catalyst

C-H Oxidation with NHPI Catalyst

General Characteristics An organocatalyst N-hydroxyphthalimide (NHPI) forms the strongly oxidizing N-oxyl radical species (PINO) in the presence of appropriate oxidizing agents. This radical is ...

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Catalytic C-H Oxidation

Catalytic C-H Oxidation

General Characteristics Catalytic C-H oxidation is a type of C-H activation reactions by which one can oxygenate unreactive C-H bonds, which are present ubiquitously in organic compounds. The C-H ...

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