General Characteristics Ketones can be synthesized by the palladium-catalyzed cross coupling between thioesters and boronic acids. The use of copper thiophene-2-carboxylate (CuTC) as an additive is ...
Tag Archives: cross-coupling
Hiyama Cross Coupling
General Characteristics The cross coupling reaction between aryl halides/triflates and organosilicon reagents (organosilanes) is generally called the Hiyama coupling. Most organosilicon reagents are ...
Buchwald-Hartwig Cross Coupling Reaction
General Characteristics -The palladium-catalyzed cross coupling between aryl halides/triflates and amines/alkoxides is known as the Buchwald-Hartwig reaction. The use of bidentate ligands (e.g. dppf, ...
Migita-Kosugi-Stille Cross Coupling Reaction
General Characteristics -The palladium-catalyzed cross coupling of organic halides or triflates with organotin compounds is known as the Migita-Kosugi-Stille coupling. -The reaction works under very ...
Negishi Cross Coupling Reaction
General Characteristics -While cross coupling reactions based on organolithium and Grignard reagents (Kumada-Tamao-Corriu cross coupling) tend to suffer from unwanted side reactions when applied to ...
Mizoroki-Heck Reaction
General Characteristics -The cross coupling reaction between an aryl/alkenyl halide and a terminal olefin in the presence of a Pd(0) catalyst to produce a substituted olefin is called the ...
Sonogashira-Hagiwara Cross Coupling Reaction
General Characteristics -The cross coupling reaction between an aryl or alkyl halide and a terminal alkyne catalyzed by the combination of Pd(0), copper iodide, and an amine is called the ...
Akira Suzuki
Akira, Suzuki (Born in 1930), is Japanese organic chemist. Suzuki was one of the recipients of Nobel prize in Chemistry 2010, with Richard Heck and Ei-ichi Negishi for their research during the 1960s ...