Barry M. Trost

Barry M. Trost

Barry M. Trost (born in 1941) is an American organic chemist, Tamaki Professor of Humanities and Sciences in the chemistry department at Stanford University. He has made great contributions to the modern synthetic organic chemistry and green chemistry.  Many widely used chemistry reactions, such as the Trost asymmetric allylic alkylation, Tsuji-Trost reaction and the Trost ligand, are named after him. Professor Trost has more than 820 scientific publications, over 320 lectures at various national and international meetings, and over 40 worldwide awards and honors.


  • Education and Experiences

1962 BS, the University of Pennsylvania

1965 Ph.D the Massachusetts Institute of Technology (Prof. H.O House) “The structure and reactivity of enolate ions”

1965 Assistant Professor,  the University of Wisconsin

1968 Associate Professor,  the University of Wisconsin

1969 Professor, the University of Wisconsin

1982 Vilas Research Professor

1987 Professor, Stanford University

1990 Stanford University, Tamaki Professor of Humanities and Sciences

  •  Awards and Honors

1967 Alfred P. Sloan Foundation Fellow

1970 Camille and Henry Dreyfus Teacher-Scholar

1975 H.I. Romnes Faculty Fellowship

1975 American-Swiss Foundation Fellow

1977 the ACS Award in Pure Chemistry

1981 the ACS Award for Creative Work in Synthetic Organic Chemistry

1981 the Baekeland Award

1983 the first Allan R. Day Award of the Philadelphia Organic Chemists’ Club

1983 the Chemical Pioneer Award of the American Institute of Chemists

1984 the Alexander von Humboldt Stiftung Award

1988 MERIT Award of NIH

1988 Hamilton Award

1989 Arthur C. Cope Scholar Award

1990 Guenther Award in the Chemistry of Essential Oils and Related Products

1990 the Dr. Paul Janssen Prize

1991 the ASSU Graduate Teaching Award

1992 Pfizer Senior Faculty Award

1993 Bing Teaching Award

1995 the ACS Roger Adams Award

1998 the Presidential Green Chemistry Challenge Award

1999 the Herbert C. Brown Award for Creative Research in Synthetic Methods

2000 the Belgian Organic Synthesis Symposium Elsevier Award

2000 the Nichols Medal

2001 the Yamada Prize

2002 the ACS Nobel Laureate Signature Award for Graduate Education in Chemistry

2004 the ACS Cope Award

2007 Thomson Scientific Laureate

2007 Kitasato Microbial Chemistry Medal

2008 Kosolapoff Award, Auburn ACS Section

2008 Nagoya Medal

2012 Fellow of the American Chemical Society

2013 Penn Chemistry Distinguished Alumni Award

2013 Excellence in Medicinal Chemistry Award, Israel Chemistry Society

  • Research

Development of transition-metal catalyzed reactions

His research focus on developing new synthetic reactions and reagents, primarily for use in synthesizing complex molecules from readily available and simple starting materials. He likes to use transition metals to carry out chemo-, regio-, diastereo- and especially enantioselective reactions.

Palladium is of great interest together with a considerable portion of the Periodic Chart including nickel, chromium, molybdenum, ruthenium, iron and tungsten.


Tsuji–Trost Allylic Alkylation


Trost Asymmetric Allylic Alkylation


Trost Oxidation

  • Atom economical synthesis

Trost is the original proponent of the atom economy[1], it means maximizing the incorporation of material from the starting materials or reagents into the final product. It is essentially pollution prevention at the molecular level.


  • References

[1] (a) Trost, B. M. Science1991254, 1471. doi:10.1126/science.1962206 (b) Trost, B. M.  Angew. Chem. Int. Ed. Engl. 199534, 259. doi:10.1002/anie.199502591 (c) Trost, B. M. Acc. Chem. Res. 200235, 695.  doi:10.1021/ar010068z S0001-4842(01)00068-1

  • Related Links

Trost Group
Barry Trost - Wikipedia
Atom Economy - Wikipedia
Trost asymmetric allylic alkylation - Wikipedia
Trost Ligand - Wikipedia


  • Photo Gallery

  • Movies

  • Related Books

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