General Characteristics First introduced in 1970’s, 2-halo-N-alkylpyridinium salts are called the Mukaiyama reagent and used for condensation reactions such as esterification and amide bond ...
Tag Archives: condensation
Classical Aldol Reaction
General Characteristics -In aldol reactions, the enol or the enolate of a ketone attacks an aldehyde or another ketone to generate a β-hydroxyketone (“aldol”). In the most classical procedure, the ...
Thorpe-Ziegler Reaction
Characteristics The reaction between a nitrile and an alkoxide base leads to the formation of a β-iminonitrile from which an α-cyanoketone is obtained by mild acid hydrolysis. This reaction is ...