General Characteristics Sulfonyl groups are stable under both acidic and basic conditions. They are also used for purposes other than protection. Commonly used groups are methanesulfonyl (Ms), ...
Tag Archives: protection of amines
Acyl Protective Groups
General Characteristics -Acyl groups are generally stable under acidic and oxidative conditions and deprotected under reductive (DIBAL, LAH, etc.) and basic (NaOH, K2CO3/MeOH etc.) conditions. ...
Carbamate Protective Groups
General Characteristics In order to tame the basicity and the high reactivity of amines during multi-step synthesis, it is common to protect them with electron-withdrawing functional groups. ...