Tag Archives: protection of amines

Sulfonyl Protective Groups

Sulfonyl Protective Groups

General Characteristics Sulfonyl groups are stable under both acidic and basic conditions. They are also used for purposes other than protection. Commonly used groups are methanesulfonyl (Ms), ...

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Acyl Protective Groups

Acyl Protective Groups

General Characteristics -Acyl groups are generally stable under acidic and oxidative conditions and deprotected under reductive (DIBAL, LAH, etc.) and basic (NaOH, K2CO3/MeOH etc.) conditions. ...

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Carbamate Protective Groups

Carbamate Protective Groups

General Characteristics In order to tame the basicity and the high reactivity of amines during multi-step synthesis, it is common to protect them with electron-withdrawing functional groups. ...

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