General Characteristics Alkylated hydroxylamines are easily oxidized by oxygen in the air. When there is a proton on the carbon α to the nitrogen, hydroxylamines are oxidized to nitrones. However, ...
Tag Archives: oxidation of alcohols
Pfitzner-Moffatt Oxidation
General Characteristics The oxidation of alcohols using the combination of DCC+Brønsted acid+DMSO is known as the Pfitzner-Moffatt oxidation. The active species of this reaction is bulkier than those ...
Albright-Goldman Oxidation
General Characteristics The Swern-type oxidation of alcohols using acetic anhydride as the activator of DMSO. The reaction times are relatively long (12-24 h). This reaction is useful for the ...
Corey-Kim Oxidation
General Characteristics The oxidation of alcohols based on the dimethylsulfide-NCS system is known as the Corey-Kim oxidation. The oxidation of primary alcohols stops at the aldehyde oxidation state. ...
Mukaiyama Oxidation
General Characteristics The Swern oxidation is relatively clean and practical but also associated with such problems as the generation of carbon monoxide and dimethylsulfide and the requirement of ...
Jones Oxidation
General Characteristics The Jones oxidation is one of the most fundamental reactions used to oxidize alcohol compounds. The reagents do not react with alkenes and alkynes and oxidize only alcohols. ...
Parikh-Doering Oxidation
General Characteristics The Parikh-Doering oxidation uses SO3•Py (a solid reagent that can be handled easily) as the activator of DMSO. This reaction is especially effective for the oxidation of ...
PCC/PDC Oxidation
General Characteristics The oxidation of alcohols by PCC (Pyridinium Chlorochromate) or PDC (Pyridinium Dichromate) works under mild conditions and can be used for compounds containing unstable ...
IBX Oxidation
General Characteristics 2-Iodoxybenzoic acid (IBX) is a mild and versatile oxidant. It can be easily prepared from 2-iodobenzoic acid and Oxone (See the Dess-Martin oxidation as reference). IBX had ...
TPAP (Ley-Griffith) Oxidation
General Characteristics The oxidation of alcohols to aldehydes or ketones can be catalyzed by TPAP (nPr4N+RuO4–; TetraPropylAmmonium Perruthenate) which is air- and moisture-tolerant and also ...