General Characteristics Disodium tetracarbonylferrate is generally referred to as the Collman reagent. It reacts with alkyl halides to give corresponding aldehydes and ketones. General References ...
Tag Archives: synthesis of aldehydes and ketones
Pfitzner-Moffatt Oxidation
General Characteristics The oxidation of alcohols using the combination of DCC+Brønsted acid+DMSO is known as the Pfitzner-Moffatt oxidation. The active species of this reaction is bulkier than those ...
Corey-Kim Oxidation
General Characteristics The oxidation of alcohols based on the dimethylsulfide-NCS system is known as the Corey-Kim oxidation. The oxidation of primary alcohols stops at the aldehyde oxidation state. ...
Malaprade Glycol Oxidative Cleavage
General Characteristics Periodic acid or sodium periodate is used to oxidatively cleave 1,2-diols, producing a pair of aldehydes or ketones. Sodium periodate also works as the reoxidant of osmium ...
Osmium Tetroxide (OsO4)
General Characteristics In the presence of re-oxidants, a catalytic amount of osmium tetroxide (OsO4) converts alkenes into cis-vicinal diols. Because of the mild reaction conditions and shortage of ...
Parikh-Doering Oxidation
General Characteristics The Parikh-Doering oxidation uses SO3•Py (a solid reagent that can be handled easily) as the activator of DMSO. This reaction is especially effective for the oxidation of ...
PCC/PDC Oxidation
General Characteristics The oxidation of alcohols by PCC (Pyridinium Chlorochromate) or PDC (Pyridinium Dichromate) works under mild conditions and can be used for compounds containing unstable ...
Dess-Martin Oxidation
General Characteristics -The oxidation of alcohols by Dess-Martin periodinane (DMP). -The reaction proceeds at room temperature, converting alcohols into aldehydes. -Reactive and mild enough to be ...