Tag Archives: nobel prize

Noyori Asymmetric Hydrogenation

Noyori Asymmetric Hydrogenation

General Characteristics The asymmetric hydrogenation of olefins and ketones catalyzed by Ru(II)-BINAP and related ruthenium complexes is called the Noyori hydrogenation. The hydrogenation of olefins ...

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Brown Hydroboration

Brown Hydroboration

General Characteristics -Alkenes can be converted into anti-Markovnikov alcohols by the Brown hydroboration, which involves regio/stereoselective syn-addition of a B-H bond to the olefin followed by ...

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Olefin Metathesis

Olefin Metathesis

General Characteristics In the presence of a metal alkylidene catalyst, two olefins combine and redistribute their fragments to give a new pair of olefins. Olefin metathesis is fundamentally an ...

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Negishi Cross Coupling Reaction

Negishi Cross Coupling Reaction

General Characteristics -While cross coupling reactions based on organolithium and Grignard reagents (Kumada-Tamao-Corriu cross coupling) tend to suffer from unwanted side reactions when applied to ...

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Mizoroki-Heck Reaction

Mizoroki-Heck Reaction

General Characteristics -The cross coupling reaction between an aryl/alkenyl halide and a terminal olefin in the presence of a Pd(0) catalyst to produce a substituted olefin is called the ...

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