General Characteristics The Minisci reaction allows for the direct functionalization of electron deficient hetero aromatic rings with carbon radicals. The radical precursor is most commonly the ...
Tag Archives: free radical
Barton-McCombie Deoxygenation
General Characteristics The free radical-mediated deoxygenation of alcohol compounds after the formation of thiocarbonyl intermediates is known as the Barton-MacCombie deoxygenation. This reaction is ...
Fukuyama Indole Synthesis
General Characteristics The Fukuyama indole synthesis is a powerful way to synthesize 3-substituted or 2,3-disubstituted indoles using a radical initiator and tributyltin hydride. The second ...
Wohl-Ziegler Bromination
General Characteristics -The Wohl-Ziegler reaction is the free radical-based bromination of allylic and benzylic positions using N-bromosuccinimide (NBS). The solvents stable under free radical ...