Tag Archives: aldehyde

Kornblum Oxidation

Kornblum Oxidation

General Characteristics Alkyl halides can be converted into the corresponding aldehydes by thermally driven displacement by DMSO followed by treatment with bases. General References ・Kornblum, N.; ...

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Betti Reaction

Betti Reaction

General Characteristics The three component condensation reaction among aldehydes, amines, and phenols is known as the Betti reaction. This reaction is the phenol version of the Mannich reaction. ...

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McFadyen-Stevens Reaction

McFadyen-Stevens Reaction

General Characteristics The thermal decomposition of acylarylsulfonylhydrazines into the corresponding aldehydes under basic conditions is known as the McFadyen-Stevens reaction. The reaction has ...

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Classical Aldol Reaction

Classical Aldol Reaction

General Characteristics -In aldol reactions, the enol or the enolate of a ketone attacks an aldehyde or another ketone to generate a β-hydroxyketone (“aldol”). In the most classical procedure, the ...

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Swern Oxidation

Swern Oxidation

General Characteristics -The oxidation of alcohols based on the dimethylsulfoxide (DMSO)-oxalyl chloride system is called the Swern oxidation. -DCC (Pfitzner-Moffatt), TFAA (modified Swern), acetic ...

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