Cativa Process for Acetic Acid Synthesis

Cativa Process for Acetic Acid Synthesis

Overall Score4.5
  • Industrial Importance
  • Scale Up of Catalytic Chemistry
  • General Characteristics

Acetic acid is produced in different ways, such as by carbonylation of methanol and oxidation of acetaldehyde or hydrocarbons. The two carbonylation processes, the rhodium-catalyzed Monsanto process and the iridium-catalyzed Cativa process, are used to supply 60% of all acetic acid in the world.

  • General References

Sunley, G. J.; Watson, D. J. Catalysis Today, 2000,  58,  293. DOI:10.1016/S0920-5861(00)00263-7

  • Reaction Mechanism

The catalytic cycle is fundamentally similar to the Monsanto process.cativa_process_2.gif

Adding an inexpensive promotor increases the catalytic efficiency. The promotor is thought to scavenge iodide ions and create a coordination site for CO, facilitating the migratory insertion step.  (Ref: J. Am. Chem. Soc. 2004126, 2847.)

  • Examples

  • Experimental Procedure

  • Experimental Tips

  • References

  • Related Reactions

Monsanto Process for Acetic Acid Synthesis

Carbonylative Cross Coupling

  • Related Books

  • External Links

Cativa Process- Wikipedia

Acetic Acid – Wikipedia

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