Overall Score4
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- Reagent Availability
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General Characteristics
The classical method to convert carboxylic acids into α-haloacyl halides using phosphorus(III) halide is known as the Hell-Volhard-Zelinsky reaction.
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General References
- Hell, C. Ber. Dtsch. Chem. Ges. 1881, 14, 891.
- Volhard, J. Liebig’s Ann. Chem. 1887, 242, 141.
- Zelinsky, N. Ber. Dtsch. Chem. Ges. 1887, 20, 2026.
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Reaction Mechanism
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Examples
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Experimental Procedure
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Experimental Tips
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References
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Related Reactions
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Related Books
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External Links
- Hell-Volhard-Zelinski Reaction (organic-chemistry.org)