Overall Score3.5			
			
		 
- Generality
 - Reagent Availability
 - Experimental User Friendliness
 - Criteria #4
 - Criteria #5
 
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General Characteristics
 
2-Oxygenated indoles can be synthesized from the corresponding secondary aryl amines and bisulfite adduct of glyoxal.
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General References
 - Hinsberg, O. Ber. Dtsch. Chem. Ges. 1888, 21, 110; 1898, 31, 250; 1908, 41, 1367.
 - Hinsberg, O.; Rosenzweig, J. Ber. Dtsch. Chem. Ges. 1894, 27, 3253
 - Burton, H. J. Chem. Soc. 1932, 546.
 
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Reaction Mechanism
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Examples
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Experimental Procedure
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Experimental Tips
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References
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Related Reactions
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Related Books
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