Barry M. Trost (born in 1941) is an American organic chemist, Tamaki Professor of Humanities and Sciences in the chemistry department at Stanford University. He has made great contributions to the modern synthetic organic chemistry and green chemistry. Many widely used chemistry reactions, such as the Trost asymmetric allylic alkylation, Tsuji-Trost reaction and the Trost ligand, are named after him. Professor Trost has more than 820 scientific publications, over 320 lectures at various national and international meetings, and over 40 worldwide awards and honors.
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Education and Experiences
1962 BS, the University of Pennsylvania
1965 Ph.D the Massachusetts Institute of Technology (Prof. H.O House) “The structure and reactivity of enolate ions”
1965 Assistant Professor, the University of Wisconsin
1968 Associate Professor, the University of Wisconsin
1969 Professor, the University of Wisconsin
1982 Vilas Research Professor
1987 Professor, Stanford University
1990 Stanford University, Tamaki Professor of Humanities and Sciences
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Awards and Honors
1967 Alfred P. Sloan Foundation Fellow
1970 Camille and Henry Dreyfus Teacher-Scholar
1975 H.I. Romnes Faculty Fellowship
1975 American-Swiss Foundation Fellow
1977 the ACS Award in Pure Chemistry
1981 the ACS Award for Creative Work in Synthetic Organic Chemistry
1981 the Baekeland Award
1983 the first Allan R. Day Award of the Philadelphia Organic Chemists’ Club
1983 the Chemical Pioneer Award of the American Institute of Chemists
1984 the Alexander von Humboldt Stiftung Award
1988 MERIT Award of NIH
1988 Hamilton Award
1989 Arthur C. Cope Scholar Award
1990 Guenther Award in the Chemistry of Essential Oils and Related Products
1990 the Dr. Paul Janssen Prize
1991 the ASSU Graduate Teaching Award
1992 Pfizer Senior Faculty Award
1993 Bing Teaching Award
1995 the ACS Roger Adams Award
1998 the Presidential Green Chemistry Challenge Award
1999 the Herbert C. Brown Award for Creative Research in Synthetic Methods
2000 the Belgian Organic Synthesis Symposium Elsevier Award
2000 the Nichols Medal
2001 the Yamada Prize
2002 the ACS Nobel Laureate Signature Award for Graduate Education in Chemistry
2004 the ACS Cope Award
2007 Thomson Scientific Laureate
2007 Kitasato Microbial Chemistry Medal
2008 Kosolapoff Award, Auburn ACS Section
2008 Nagoya Medal
2012 Fellow of the American Chemical Society
2013 Penn Chemistry Distinguished Alumni Award
2013 Excellence in Medicinal Chemistry Award, Israel Chemistry Society
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Research
Development of transition-metal catalyzed reactions
His research focus on developing new synthetic reactions and reagents, primarily for use in synthesizing complex molecules from readily available and simple starting materials. He likes to use transition metals to carry out chemo-, regio-, diastereo- and especially enantioselective reactions.
Palladium is of great interest together with a considerable portion of the Periodic Chart including nickel, chromium, molybdenum, ruthenium, iron and tungsten.
Tsuji–Trost Allylic Alkylation
Trost Asymmetric Allylic Alkylation
Trost Oxidation
- Atom economical synthesis
Trost is the original proponent of the atom economy[1], it means maximizing the incorporation of material from the starting materials or reagents into the final product. It is essentially pollution prevention at the molecular level.
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References
[1] (a) Trost, B. M. Science, 1991, 254, 1471. doi:10.1126/science.1962206 (b) Trost, B. M. Angew. Chem. Int. Ed. Engl. 1995, 34, 259. doi:10.1002/anie.199502591 (c) Trost, B. M. Acc. Chem. Res. 2002, 35, 695. doi:10.1021/ar010068z S0001-4842(01)00068-1
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Related Links
Trost Group
Barry Trost - Wikipedia
Atom Economy - Wikipedia
Trost asymmetric allylic alkylation - Wikipedia
Trost Ligand - Wikipedia
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Photo Gallery
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Movies
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Related Books
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