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McFadyen-Stevens Reaction

McFadyen-Stevens Reaction

General Characteristics The thermal decomposition of acylarylsulfonylhydrazines into the corresponding aldehydes under basic conditions is known as the McFadyen-Stevens reaction. The reaction has ...

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Kolbe Electrolysis

Kolbe Electrolysis

General Characteristics The decarboxylation of carboxylic acids and dimerization of the R group under electrolytic conditions is known as the Kolbe electrolysis. General References Kolbe, H. Ann. ...

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Hinsberg Oxindole Synthesis

Hinsberg Oxindole Synthesis

General Characteristics 2-Oxygenated indoles can be synthesized from the corresponding secondary aryl amines and bisulfite adduct of glyoxal. General References Hinsberg, O. Ber. Dtsch. Chem. Ges. ...

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Camps Quinoline Synthesis

Camps Quinoline Synthesis

General Characteristics The basic treatment of ortho-acylaminoacetophenones leads to cyclocondensation, producing hydroxyquinolines. The experimenter needs to be aware of possible isomer formation. ...

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Benzyne

Benzyne

General Characteristics The dehydrogenated form of benzene (the benzene minus two hydrogen atoms) is commonly called benzyne. There are three regioisomers. o-Benzyne, in which the ortho hydrogens are ...

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Baldwin’s Rule

Baldwin’s Rule

General Characteristics The rate of ring closing reactions is largely influenced by how easily the orbitals can interact and overlap at the reacting parts of the molecule. The empirical rule that ...

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Fenton Reaction

Fenton Reaction

General Characteristics The hydroxyl radical generated from H2O2 in the presence of iron(II) is used to promote various decomposition reactions. Copper(I) is known to have a similar property as well. ...

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