General Characteristics -A secondary alcohol reacts with diethyl azodicarboxylate (DEAD), triphenylphosphine (Ph3P), and benzoic acid to give a corresponding benzoyloxy derivative with the inversion ...
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Benzyl (Bn) Protective Group
General Characteristics -Benzyl group (Bn) is stable towards both acids and bases and is a highly general protecting group. -Base sensitive compounds can be protected using BnOC(=NH)CCl3 under acidic ...
Silyl Protective Groups
General Characteristics -Serving as effective protective groups for alcohols, silyl ethers are used extensively in laboratory scale synthesis. -At least two of the three R’ groups are the same group, ...