Characteristics Ichikawa Allylcyanate rearrangement is [3.3] sigmatropic rearrangement of allyl cyanates to isocyanate. The rearrangement begins with dehydration of allyl carbamate by Appel ...
Posts by Category: Reactions
Singlet Oxygen
Characteristics Since molecular oxygen exists in a triplet ground state (3O2),the spin conservation rule restricts its transforma- tions to radical-type reactions, which are normally quite ...
1,3-Dipolar Cycloaddition of Nitrile Oxide
Characteristics Nitrile oxides, R-C≡N+-O- are organic compounds which contain a monovalent functional group -CNO, which bound directly to a carbon atom of the organic moiety of a molecule. Most ...
1,3-Dipolar Cycloaddition of Nitrone
Characteristics The 1,3-dipolar cycloaddition of nitrones, a kind of 1,3-dipole to unsaturated (C–C double or triple bond) compounds is one of the useful synthetic method for preparing isoxazole, ...
Trimethylenemethane(TMM) Cycloaddition
Characteristics Trimethylenemethane (TMM) [3 + 2] cycloadditions provide direct routes to functionalized cyclopentanes. This reaction has been shown to be a highly chemo-, regio-, and ...
Negishi Carbometalation
Characteristics Ngishi carbometalation is shown to involve one-step syn-addition of a Me–Zr bond to terminal alkynes in an anti-Markovnikov manner followed by Zr-to-Al transmetalation on the ...
Electrophilic Trifluoromethylation
Characteristics Efficient transfer of the trifluoromethyl group from a reagent to a target molecule is key for the reaction, and the reagents are classified according to their radical, nucleophilic ...
Crabbe Allene Synthesis
Characteristics Crabbe allene synthesis (Crabbe homologation) is Cu-cataylzed synthesis of terminal allene compounds via homologation of acetylene precursors in the presence of diisopropylamine and ...
MIDA boronate
Characteristics N-methyliminodiacetic acid (MIDA) is very useful protecting group for boronic acid and forms stable (more stable that the free acid) boronates which are readily prepared from the ...
Amii Trifluoromethylation
Characteristics Amii trifluoromethylation is a the synthesis of trifluoromethylarenes from aryl/heteroaryliodides with CF3SiEt3 by Cu-catalsis. Selective introduction of trifluoromethyl ...