Posts by Category: Reactions

Crabbe Allene Synthesis

Crabbe Allene Synthesis

Characteristics Crabbe allene synthesis (Crabbe homologation) is Cu-cataylzed synthesis of terminal allene compounds via homologation of acetylene precursors in the presence of diisopropylamine and ...

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MIDA boronate

MIDA boronate

Characteristics N-methyliminodiacetic acid (MIDA) is very useful protecting group for boronic acid and forms stable (more stable that the free acid) boronates which are readily prepared from the ...

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Amii Trifluoromethylation

Amii Trifluoromethylation

Characteristics Amii trifluoromethylation is a the synthesis of trifluoromethylarenes from  aryl/heteroaryliodides with CF3SiEt3 by Cu-catalsis. Selective introduction of trifluoromethyl ...

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Kharasch-Sosnovsky Oxidation

Kharasch-Sosnovsky Oxidation

Characteristics Kharasch and Sosnovsky reported the allylic oxidation of alkenes to give racemic allylic benzoate’s. This could be achieved efficiently using a tert-butyl perester as the ...

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Kharasch Addition

Kharasch Addition

Characteristics Kharasch addition is  the addition of polyhalogenated compounds to alkenes. This reaction was first reported in the 1940s by Kharasch[a] and today is known as Kharasch addition or ...

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Boyer-Schmidt-Aube Rearrangement

Boyer-Schmidt-Aube Rearrangement

Characteristics Boyer-Schmidt-Aube Rearrangement is the Lewis acid-mediated reactions of simple ketones with alkyl azides.  It has been shown that the Schmidt reaction of alkyl azides, a reaction ...

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Barluenga’s Reagent

Barluenga’s Reagent

 Characteristics Bis(pyridine)iodonium tetrafluoroborate (IPy2BF4; CAS  15656-28-7) is an iodinating and oxidizing reagent[b], which was developed by José Barluenga.[a] Examples as an iodinating ...

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