Posts by Category: Reactions

Minisci Reaction

Minisci Reaction

Characteristics   Literature reference ・Minisci, F.; Bernardi, R.; Bertini, F.; Galli, R.; Perchinummo, M. Tetrahedron 1971, 27, 3575. DOI:10.1016/S0040-4020(01)97768-3 ・Minisci, F.; Vismara, ...

Read more
Thorpe-Ziegler Reaction

Thorpe-Ziegler Reaction

Characteristics The reaction between a nitrile and an alkoxide base leads to the formation of a β-iminonitrile from which an α-cyanoketone is obtained by mild acid hydrolysis. This reaction is ...

Read more
Hydration of Alkyne

Hydration of Alkyne

Characteristics Hydration of alkynes is simply the addition of H2O in the presence of Lewis acids. The hydration of alkynes has been extensively studied for more than 100 years. This reation allows ...

Read more
Singlet Oxygen

Singlet Oxygen

Characteristics Since molecular oxygen exists in a triplet ground state (3O2),the spin conservation rule restricts its transforma- tions to radical-type reactions, which are normally quite ...

Read more
Negishi Carbometalation

Negishi Carbometalation

Characteristics Ngishi carbometalation is shown to involve one-step syn-addition of a Me–Zr bond to terminal alkynes in an anti-Markovnikov manner followed by Zr-to-Al transmetalation on the ...

Read more