Characteristics The reaction between a nitrile and an alkoxide base leads to the formation of a β-iminonitrile from which an α-cyanoketone is obtained by mild acid hydrolysis. This reaction is ...
Author Archive
Direct Hydroboration of B=B Bonds: A Mild Strategy for the Proliferation of B=B Bonds
Braunschweig, H.; Dewhurst, R. D.; Hcrl, C.; Phukan, A. K.; Pinzner, F.; Ullrich, S. Angew. Chem. Int. Ed. 53, 2014. Early View. DOI: 10.1002/anie.201309325 Synthetic access to electron-precise boron ...
Inorganic-Base-Mediated Hydroamination of Alkenyl Oximes for the Synthesis of Cyclic Nitrones
Peng, X.; Tong, M. K. B.; Hirao,H.; Chiba, S. Angew. Chem. Int. Ed. 53, 2014. 1959. DOI: 10.1002/anie.201308617 A method based on hydroamination mediated by inorganic base was developed for the ...
Oxidant-Free Conversion of Cyclic Amines to Lactams and H2 Using Water As the Oxygen Atom Source
Khusnutdinova, J. R.; Ben-David, Y.; Milstein, D. J. Am. Chem. Soc. 136, 2014. 2998. DOI: 10.1021/ja500026m Direct conversion of cyclic amines to lactams utilizing water as the only reagent is ...
Hydration of Alkyne
Characteristics Hydration of alkynes is simply the addition of H2O in the presence of Lewis acids. The hydration of alkynes has been extensively studied for more than 100 years. This reation allows ...
Dragmacidin D
The dragmacidins represent an emerging class of bioactive marine natural products obtained by an exhaustive set of protocols from a number of deep water sponges including Dragmacidon, Halicortex, ...
Selective Transformation with Tin Acetal
Characteristics Typically, the 1,2-diol is treated with Bu2SnX, where X = O or (OMe), with removal (azeotropic or desiccant) of either H2O or MeOH to afford the requisite stannylidenes (“tin ...
#6 Prof. Jun Terao: Synthesizing electronic circuits
The sixth interview of this series is with Professor Jun Terao from the Graduate School of Engineering at Kyoto University, as suggested by Professor Kenichiro Itami at our second Chem-Station ...
Ichikawa Allylcyanate Rearrangement
Characteristics Ichikawa Allylcyanate rearrangement is [3.3] sigmatropic rearrangement of allyl cyanates to isocyanate. The rearrangement begins with dehydration of allyl carbamate by Appel ...
Singlet Oxygen
Characteristics Since molecular oxygen exists in a triplet ground state (3O2),the spin conservation rule restricts its transforma- tions to radical-type reactions, which are normally quite ...