Asadirad, A. M.; Boutault, S.; Erno, Z.; Branda, N. R. J. Am. Chem. Soc. 2014. ASAP DOI: 10.1021/ja500496n A thermally remendable polymer was synthesized by the Diels–Alder reaction between ...
Author Archive
1,3-Dipolar Cycloaddition of Nitrile Oxide
Characteristics Nitrile oxides, R-C≡N+-O- are organic compounds which contain a monovalent functional group -CNO, which bound directly to a carbon atom of the organic moiety of a molecule. Most ...
Photopharmacology: Beyond Proof of Principle
Velema, W. A.; Szymanski, W.; Feringa, B.L. 2014.ASAP (perspective) DOI: 10.1021/ja413063e Pharmacotherapy is often severely hindered by issues related to poor drug selectivity, including side ...
1,3-Dipolar Cycloaddition of Nitrone
Characteristics The 1,3-dipolar cycloaddition of nitrones, a kind of 1,3-dipole to unsaturated (C–C double or triple bond) compounds is one of the useful synthetic method for preparing isoxazole, ...
Trimethylenemethane(TMM) Cycloaddition
Characteristics Trimethylenemethane (TMM) [3 + 2] cycloadditions provide direct routes to functionalized cyclopentanes. This reaction has been shown to be a highly chemo-, regio-, and ...
Akira Suzuki
Akira, Suzuki (Born in 1930), is Japanese organic chemist. Suzuki was one of the recipients of Nobel prize in Chemistry 2010, with Richard Heck and Ei-ichi Negishi for their research during the 1960s ...
Robert B. Merrifield
Robert Bruce Merrifield, (1921-) is an American biochemist who won the 1984 Nobel Prize in chemistry for his method of producing peptides and proteins. He revolutionized the study of these complex ...
Negishi Carbometalation
Characteristics Ngishi carbometalation is shown to involve one-step syn-addition of a Me–Zr bond to terminal alkynes in an anti-Markovnikov manner followed by Zr-to-Al transmetalation on the ...
Electrophilic Trifluoromethylation
Characteristics Efficient transfer of the trifluoromethyl group from a reagent to a target molecule is key for the reaction, and the reagents are classified according to their radical, nucleophilic ...
George Andrew Olah
George Andrew Olah (born in 1927, ) is a Hungarian and Americal chemist. He was awarded with the Nobel Prize in Chemistry 1994 for his work involving generation and reactivity of carbocations via ...