General Characteristics Acid- or base-promoted classical aldol reactions give a complex mixture of products because of the reversibility and the difficulty of controlling the enolate geometry. In the ...
Daily Archives: May 4, 2014
Partial Reduction of Esters, Amides, and Nitriles with Metal Hydride Reagents
General Characteristics Esters, amides, and nitriles are reduced to aldehydes (without overreduction) using appropriate metal hydride reagents at low temperatures. DIBAL and Red-Al are used commonly ...