General Characteristics The one-carbon homologation of boronate compounds using α-halocarbanions is called the Matteson reaction. The rearrangement of the intermediate can be rendered stereoselective ...
Yearly Archives: 2016
Protecting Groups for Boronic Acids
General Characteristics Boronic acids are stable towards air and moisture and are usually solids that can be handled easily. Even though they are undoubtedly an important class of reagents used for ...
Newman-Kwart Rearrangement
General Characteristics The thermal rearrangement of O-thiocarbamates into S-thiocarbamates is an effective way to synthesize thiophenols from phenols. The rearrangement usually requires very high ...
Sonication in Organic Synthesis
General Characteristics Even though the rate acceleration effect of sonication has been long known, its application to organic synthesis is becoming popular only relatively recently. The development ...
Hanessian-Hullar Reaction
General Characteristics By the treatment with N-bromosuccinimide (NBS), benzylidene acetals can be oxidatively opened. The bromine ends up on the less hindered side of the two hydroxyl groups. ...
Mukaiyama Hydration
General Characteristics The hydration of alkenes using catalytic cobalt and stoichiometric silane under aerobic conditions was developed by Mukaiyama. The regioselectivity follows the ...
Wulff-Dotz Reaction
General Characteristics The synthesis of phenols by reacting [alkoxy(vinyl)carbene]pentacarbonylchromium complexes (Fischer carbene complex) with alkenes is called the Wulff-Dotz reaction. The ...
Povarov Reaction
General Characteristics The condensation of aldehydes, anilines, and electron-rich alkenes provides access to substituted tetrahydroquinoline skeletons. This is a type of three-component reaction ...
Visible Light Photoredox Catalyst
General Characteristics Transition metal complexes such as ruthenium(II) polypyridyl and iridium(III) phenylpyridyl are known to function as photoredox catalysts under irradiated conditions with ...
Minisci Reaction
General Characteristics The Minisci reaction allows for the direct functionalization of electron deficient hetero aromatic rings with carbon radicals. The radical precursor is most commonly the ...