General Characteristics -In cross aldol reactions, the donor carbonyl compound is deprotonated completely by a strong base like LDA to preform its metal enolate, which prevents self-condensation upon ...
Daily Archives: April 1, 2014
Buchwald-Hartwig Cross Coupling Reaction
General Characteristics -The palladium-catalyzed cross coupling between aryl halides/triflates and amines/alkoxides is known as the Buchwald-Hartwig reaction. The use of bidentate ligands (e.g. dppf, ...
TPAP (Ley-Griffith) Oxidation
General Characteristics The oxidation of alcohols to aldehydes or ketones can be catalyzed by TPAP (nPr4N+RuO4–; TetraPropylAmmonium Perruthenate) which is air- and moisture-tolerant and also ...