General Characteristics Phenols can be converted into thiophenols through thermal rearrangement of corresponding thiocarbamates or thiocarbonates followed by hydrolysis. General References ...
Monthly Archives: May 2016
Catellani Reaction
General Characteristics The Catellani reaction is a type of three component reaction in which the Mizoroki-Heck reaction and ortho C-H alkylation with alkyl halide occur concomitantly in the presence ...
Markovnikov’s Rule
General Characteristics In electrophilic addition reactions of alkenes, the electrophiles (electronically positive atoms or groups) generally bond with the carbon that has more hydrogen atoms. This ...
Matteson Reaction
General Characteristics The one-carbon homologation of boronate compounds using α-halocarbanions is called the Matteson reaction. The rearrangement of the intermediate can be rendered stereoselective ...
Protecting Groups for Boronic Acids
General Characteristics Boronic acids are stable towards air and moisture and are usually solids that can be handled easily. Even though they are undoubtedly an important class of reagents used for ...
Newman-Kwart Rearrangement
General Characteristics The thermal rearrangement of O-thiocarbamates into S-thiocarbamates is an effective way to synthesize thiophenols from phenols. The rearrangement usually requires very high ...
Sonication in Organic Synthesis
General Characteristics Even though the rate acceleration effect of sonication has been long known, its application to organic synthesis is becoming popular only relatively recently. The development ...