General Characteristics The acylation of amine N-oxides with acid chlorides or acid anhydrides leads to bond fragmentation at the α-position, yielding the corresponding amides and aldehydes as ...
Tag Archives: N-oxide
Synthesis of N-Oxide
General Characteristics Amines are susceptible to oxidation. Tertiary amines are oxidized to give N-oxides. Secondary amines having proton(s) at the α-position are oxidized to nitrones. The ...