A heavy drug is a drug labeled with deuterium (2H, D).[1] By replacing C-H bonds at metabolic sites in drug molecules with more stable C-D bonds, metabolism can be slowed down. This deuteration makes ...
Tag Archives: deuterium labeling
Deuterium Labeling Reaction
General Characteristics The exchange of hydrogen with its isotope deuterium has a wide range of useful applications. The underlying principle is that while replacement of hydrogen with deuterium ...