General Characteristics The Simmons-Smith cyclopropanation can be rendered asymmetric by using the chiral boronic acid ester as a reagent. An allylic hydroxyl group is needed in substrates as a ...
Tag Archives: cyclopropanation
Cyclopropanation with Metal Carbenoids
General Characteristics In the presence of metal catalysts, diazo compounds decompose to generate metal carbenoid species, which react with olefins to give cyclopropanes. Metal carbenoids also react ...