General Characteristics In the Hofmann rearrangement, primary amides rearrange into isocyanates upon treatment with halogens and bases and are ultimately converted into primary amines with one-carbon ...
Tag Archives: synthesis of primary amines
Gabriel Amine Synthesis
General Characteristics The synthesis of primary amines by way of alkylation of phthalimide is called the Gabriel amine synthesis. The use of DMF as the solvent generally increases the yield by ...