Tag Archives: directed metalation

Directed Ortho Metalation

Directed Ortho Metalation

General Characteristics Ortho-selective functionalization of aromatic compounds is possible for the substrates having appropriate directing atoms or groups. Directed ortho metalation (abbreviated as ...

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Knochel-Hauser Base

Knochel-Hauser Base

General Characteristics TMPMgCl-LiCl is known as the Knochel-Hauser base and a useful reagent for directed metalation of aromatic compounds. The metalation of aromatic compounds are conventionally ...

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