Monthly Archives: March 2015

Nucleophilic Fluoroalkylation

Nucleophilic Fluoroalkylation

General Characteristics When one wants to introduce perfluoroalkyl groups onto carbonyl groups by nucleophilic addition, she/he needs fluorine-containing organometallic reagents. However, these ...

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Takeda Olefination

Takeda Olefination

General Characteristics The olefination of thioacetals via generation of organotitanium intermediates using divalent titanocene reagents is known as the Takeda olefination. The titanocene reagent ...

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Aza-Wittig Reaction

Aza-Wittig Reaction

General Characteristics Nucleophilic phosphorus reagents such as triphenylphosphine react with azides to generate, via the Staudinger reaction, N-P ylide (iminophosphorane) intermediates, which react ...

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Takai-Lombardo Reaction

Takai-Lombardo Reaction

General Characteristics In the Takai olefination, carbonyl compounds are olefinated using organotitanium reagents derived from gem-dihaloalkanes. Whereas most of other olefination reactions are ...

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Fine-tuned Supramolecular Polymerization

Fine-tuned Supramolecular Polymerization

A class of polymeric materials called supramolecular polymers is drawing an attention in recently years. In contrast to “conventional” polymers, which consist of covalently linked monomeric units, ...

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