Manuel Alcarazo

Manuel Alcarazo

18 May, 2017 / by / in Chemists, Organic
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Manuel Alcarazo (born in 1978, Spain) is a Professor at the University of Göttingen. (The photo is quoted from the laboratory HP)

  • Education and Experiences

2005 PhD, the Instituto de Investigaciones Químicas (CSIC) (Dr. José M. Lassaletta)

2005-2008 Postdoc, the Max-Planck-Institut für Kohlenforschung in Mülheim/Ruhr (Prof. Dr. Alois Fürstner)

2009-2015 Independent Junior Group Leader, the Max-Planck-Institut für Kohlenforschung in Mülheim/Ruhr

2015- Full Professor (W3) of Organic Chemistry, Institute of Organic and Biomolecular Chemistry, University of Göttingen

2017- Director of the Institute of Organic and Biomolecular Chemistry, University of Göttingen

  • Research

Development of novel cationic phosphorus ligands

The phosphorus ligand having an α-cation forms a metal complex with a high π acidity due to a strong induction effect of the substituent. Prof. Alcarazo designs and synthesizes a ligand in which a cationic heterocyclic compound is bound to phosphorus. He applies it to various catalytic reactions [1].

Recently, his group succeeded in the development of chiral phosphorus ligands and its application to catalytic asymmetric synthesis of optically active helicene derivatives [2].

Creation of new reagents utilizing isoelectronicity

Prof. Alcarazo was inspired by reagents in an isolobal relationship, and developed a novel hypervalent sulfur reagent that behaves like a hypervalent iodine reagent [3].

from ref 3

  • Related Books

[amazonjs asin=”1118839838″ locale=”US” title=”Ligand Design in Metal Chemistry: Reactivity and Catalysis”]

  • References

  1. Alcarazo, M. Chem. Res. 2016, 49, 1797. DOI: 10.1021/acs.accounts.6b00262
  2. “Enantioselective Synthesis of [6]Carbohelicenes” Gonzaĺez-Fernańdez, E.; Nicholls, L. D. M.; Schaaf, L. D.; Fares̀, C.; Lehmann, C. W.; Alcarazo M. J. Am. Chem. Soc. 2017, 139, 1428. DOI: 10.1021/jacs.6b12443
  3. “Dihalo(imidazolium)sulfuranes: A Versatile Platform for the Synthesis of New Electrophilic Group-Transfer Reagents” Talavera, G.; Peña, J.; Alcarazo, M.  J. Am. Chem. Soc. 2015, 137, 8704. DOI: 10.1021/jacs.5b05287
  4. ”Author Profile – Manuel Alcarazo” Angew. Chem. Int. Ed. 2013, 52, 6362. DOI: 10.1002/anie.201209931

 

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