Boyland-Sims Oxidation

Boyland-Sims Oxidation

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Anilines can be converted into aminophenols by the reaction called the Boyland-Sims oxidation. Ortho-hydroxylated products are usually obtained preferentially.

The oxidation of phenols under the same conditions is called the Elbs persulfate oxidation.

  • General References

  •  Boyland, E. et al. J. Chem. Soc. 1953, 3623. DOI: 10.1039/JR9530003623
  •  Boyland, E.; Sims, P. J. Chem. Soc. 1954, 980. DOI: 10.1039/JR9540000980
  •  Behrman, E. J. Org. React. 1988, 35, 421.
  •  Boyland, E.; Sims, P.; Williams, D. C. Biochem. J. 195662, 546.

Reviews

  • Reaction Mechanism

Reference: Behrman, E. J. J. Org. Chem. 1992, 57, 2266. DOI: 10.1021/jo00034a016

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Boyland-Sims Oxidation – Wikipedia

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